Source: http://news.feedzilla.com/en_us/stories/politics/top-stories/306313381?client_source=feed&format=rss
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ASUS GTX 670 DirectCU Mini set at $399 with May 20th release, up for pre-order (video)
ASUS' GeForce GTX 670 DirectCU Mini graphics card first broke cover in April without a price or concrete release date, but now Newegg has dished out just those details along with extra specs. Loaded with 1,344 CUDA cores and 2GB of 256-bit GDDR5 RAM, the silicon boats a base clock of 928Mhz and a boost speed of 1,006MHz. The 6.7-inch-long hardware bound for diminutive -- or even full-size -- PCs rings up at $399, and is slated for availability on May 20th. Click the source link below to pre-order the dual-slot dwarf or head past the break for the retailer's unboxing video.
[Thanks, Cody]
Filed under: Desktops
Source: Newegg
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Marshals: Tiger lied about Garcia incident
Marshals say Tiger lied about talking to the course marshals before he pulled a club and distracted Sergio Garcia at the Players Championship. If Tiger Woods lied, it's the third incident involving his integrity in recent weeks.
Sergio Garcia, of Spain, left, shakes hands with Tiger Woods at the conclusion of the third round of The Players championship golf tournament in Ponte Vedra Beach, Fla. Course marshals now dispute Tiger Woods' version of an incident that distracted Garcia during one swing.
(AP Photo/Gerald Herbert)
EnlargeTiger?Woods has faced more scrutiny that any other golfer from his generation. Maybe ever. Just not this variety.
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Now it's his integrity on the golf course that's being questioned.
Tiger Woods won The Players Championship on Sunday for his fourth victory this year. Making it even more memorable, Woods ended his public spat with Sergio Garcia by posing with the crystal trophy. They were tied with two holes to play, and Garcia hit three shots in the water.
That all seems like B-material compared with the buzz over course marshals statements that contradict Wood's version of events with Garcia. Essentially, they say he lied.? And then there's the drop Woods took on the 14th hole of the final round.
He hit what he called a "pop-up hook" with a 3-wood from the tee, and the ball landed in the water left of the fairway. Consulting with Casey Wittenberg, he dropped it some 255 yards short of the green. Woods then hit a remarkable shot short of the green, pitched on and missed a 6-foot putt to take double bogey.
The Internet has been alive with video showing the ball's flight on the 14th, along with analysis dissecting what was and was not said by a TV analyst, and seemingly endless theories how the ball could possibly have crossed land where Woods took his drop.
The chatter won't stop, even though there is nowhere to go with it. Consider this statement put out by Mark Russell, the tour's vice president of competition: "Without definitive evidence, the point where Woods' ball last crossed the lateral water hazard is determined through best judgment by Woods and his fellow competitor," the statement said.
Woods conferred with Wittenberg, his playing partner.
"I saw it perfectly off the tee," Wittenberg said. "I told him exactly where I thought it crossed, and we all agreed. So he's definitely great on that."
And if video suggests otherwise?
Decision 26-1/17 says a penalty would not be appropriate because it comes down to an honest judgment.
Of course, this might not be that big of an issue except that Woods in his most recent tournament ? the Masters ? was guilty of taking an illegal drop on the 15th hole at Augusta National. He eventually was docked two shots, but spared disqualification by the Masters because officials said they erred in not talking to Woods about the drop before he signed his scorecard. The rules back up that decision, though this one (Rule 33-7) is subject to interpretation. It could have gone either way.
That debate rages on. Should he have withdrawn for his own benefit? Did the Masters bail him out? Meanwhile, Adam Scott has a green jacket at his place in The Bahamas and he apparently wears it every morning. Good for him.
Back to Sawgrass, where there was that Saturday incident with Garcia which was one case where Woods shared some responsibility.
Source: http://rss.csmonitor.com/~r/feeds/csm/~3/UIyd1pHVKTE/Marshals-Tiger-lied-about-Garcia-incident
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Wanderlei Silva responds to Chael Sonnen?s callout in an extremely gross way
"Jon Jones and Anderson Silva have been too nice to Chael. I want to suck his blood. I want to smell it. Not just fight ? I want to hurt him. Chael is a joke, man. He?s going to be second forever. He?s never going to be first," Silva said to Ariel Helwani.
MMA is a bloody sport, and we're used to seeing blood cover fighters, their clothes and canvases. But we are not vampires, sparkly or otherwise. Blood sucking, Wanderlei? Really? Perhaps Wand is a fan of the "Twilight" novels, but let's keep the vampire aspects out of MMA and in young adults novels, OK?
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Castro?s new legal team says he?ll plead not guilty
Lawyers for Ariel Castro say he'll plead not guilty to charges of kidnapping and raping three women while holding them captive for a decade in his west Cleveland home.
"The initial portrayal by the media has been one of a 'monster' and that's not the impression that I got when I talked to him for three hours," Craig Weintraub, one of Castro's lawyers, told Cleveland's WKYC-TV late Tuesday.
The 52-year-old is being held on an $8 million bond in Cuyahoga County Jail and is under a suicide watch.
"He doesn't have a television, doesn't have radio, doesn't have magazines, no access to newspapers," Jaye Schlachet, another Castro lawyer, said. "He's completely isolated from society."
[Related: Castro brothers break silence on Cleveland case]
Castro is suspected of kidnapping Michelle Knight in 2002, Amanda Berry in 2003 and Gina DeJesus in 2004, and then holding them captive in his west Cleveland home. DNA tests confirm he fathered a daughter with Berry in 2006.
"I can tell you that Mr. Castro is extremely committed to the well-being and positive future for his daughter, who he loves dearly," Schlachet said. "And if people find that to be a disconnect from what he's alleged to have done, then the people will just have to deal with it. We just know how he feels about his little girl."
Castro's attorneys say that how he came into contact with the women will be revealed "as the case progresses." And they say they may seek a change of venue to get a fair trial.
"I know the media wants to jump to conclusions, and all the people in the community want to say terrible things about the person who's accused," Schlachet added. "We are not even at the beginning of the process. If this was a marathon race, we're not even at the starting line yet."
Source: http://news.yahoo.com/blogs/lookout/castro-plead-not-guilty-123152315.html
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Study finds plasmin -- delivered through a bubble -- more effective than tPA in busting clots
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Public release date: 15-May-2013[ | E-mail |
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University of Cincinnati Academic Health Center
Cincinnati researchers use liposomes, ultrasound waves to deliver targeted therapy
CINCINNATIA new study from the University of Cincinnati has found that, when delivered via ultrasound, the natural enzyme plasmin is more effective at dissolving stroke-causing clots than the standard of care, recombinant tissue plasminogen activator (rt-PA).
The novel delivery method involved trapping plasmin into bubble-like liposomes, delivering them to the clot intravenously and bursting it via ultrasound. That method is necessary, says UC associate professor of emergency medicine George "Chip" Shaw III, MD, PhD, because plasmin cannot be delivered through traditional methods. Intravenous delivery of rt-PA is designed to solve that problem by catalyzing the conversion of existing plasminogen inside the body to plasmin, which in turn degrades blood clots.
"Plasmin is the enzyme that actually chews up the fibrin in clots," says Shaw. "The problem is you can only give plasmin inter-arterially, which has safety risks and takes longer to deliver. IV therapy is always easier and quicker, but if you give plasmin intravenously, the body inhibits it immediately. If you can encapsulate it, it doesn't get inhibited and you can target it to the clot."
In their in-vitro study, Shaw and researchers Madhuvathi Kandadai, PhD, and Jason Meunier, PhD, enclosed plasmin and a gas bubble inside a liposome. They then delivered the liposome to a clot in an in-vitro lab clot model and dissolved it using ultrasound waves, thus delivering the plasmin enzyme to the clot. After 30 minutes, clots treated with plasmin showed significantly greater breakdown than clots treated with rt-PA.
They worked with colleague Christy Holland, PhD, professor in UC's cardiovascular diseases division, to develop the technique. As director of the Image-guided Ultrasound Therapeutics Laboratories at UC, Holland has studied the use of liposomes and ultrasound to deliver drugs in a less invasive, more targeted fashion.
The standard of care for acute ischemic stroke is intravenous delivery of U.S. Food and Drug Administration-approved rt-PA within three hours of stroke onset. Ischemic stroke is the most common type of stroke, accounting for about 87 percent of all stroke cases.
But Shaw says there is a "critical need" for a safer and more effective thrombolytic, as rt-PA carries a risk of bleeding. Intracranial hemorrhage currently occurs in 6 percent of patients receiving rt-PA therapy.
"Previous in vivo studies have demonstrated better safety of plasmin as compared with rt-PA," he says. "Currently, intra-arterial plasmin is undergoing clinical trials. Our next step is to work on targeting the liposome by putting antibodies on its surface that will stick it to the clot. We also want to improve the efficiency of encapsulating the plasmin in the liposome. Right now, about 15 percent of the plasmin gets into the liposomewe're aiming for 50 percent."
###
Kandadai, a postdoctoral fellow in the UC Department of Emergency Medicine, will present the abstract, "Plasmin loaded echogenic liposomes: A Novel Thrombolytic," at the Society for Academic Emergency Medicine annual meeting May 14-18 in Atlanta. Meunier, a research assistant professor of emergency medicine, is also a co-author.
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AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.
Public release date: 15-May-2013[ | E-mail |
Share ] Contact: Katy Cosse
kcosse@gmail.com
513-309-3180
University of Cincinnati Academic Health Center
Cincinnati researchers use liposomes, ultrasound waves to deliver targeted therapy
CINCINNATIA new study from the University of Cincinnati has found that, when delivered via ultrasound, the natural enzyme plasmin is more effective at dissolving stroke-causing clots than the standard of care, recombinant tissue plasminogen activator (rt-PA).
The novel delivery method involved trapping plasmin into bubble-like liposomes, delivering them to the clot intravenously and bursting it via ultrasound. That method is necessary, says UC associate professor of emergency medicine George "Chip" Shaw III, MD, PhD, because plasmin cannot be delivered through traditional methods. Intravenous delivery of rt-PA is designed to solve that problem by catalyzing the conversion of existing plasminogen inside the body to plasmin, which in turn degrades blood clots.
"Plasmin is the enzyme that actually chews up the fibrin in clots," says Shaw. "The problem is you can only give plasmin inter-arterially, which has safety risks and takes longer to deliver. IV therapy is always easier and quicker, but if you give plasmin intravenously, the body inhibits it immediately. If you can encapsulate it, it doesn't get inhibited and you can target it to the clot."
In their in-vitro study, Shaw and researchers Madhuvathi Kandadai, PhD, and Jason Meunier, PhD, enclosed plasmin and a gas bubble inside a liposome. They then delivered the liposome to a clot in an in-vitro lab clot model and dissolved it using ultrasound waves, thus delivering the plasmin enzyme to the clot. After 30 minutes, clots treated with plasmin showed significantly greater breakdown than clots treated with rt-PA.
They worked with colleague Christy Holland, PhD, professor in UC's cardiovascular diseases division, to develop the technique. As director of the Image-guided Ultrasound Therapeutics Laboratories at UC, Holland has studied the use of liposomes and ultrasound to deliver drugs in a less invasive, more targeted fashion.
The standard of care for acute ischemic stroke is intravenous delivery of U.S. Food and Drug Administration-approved rt-PA within three hours of stroke onset. Ischemic stroke is the most common type of stroke, accounting for about 87 percent of all stroke cases.
But Shaw says there is a "critical need" for a safer and more effective thrombolytic, as rt-PA carries a risk of bleeding. Intracranial hemorrhage currently occurs in 6 percent of patients receiving rt-PA therapy.
"Previous in vivo studies have demonstrated better safety of plasmin as compared with rt-PA," he says. "Currently, intra-arterial plasmin is undergoing clinical trials. Our next step is to work on targeting the liposome by putting antibodies on its surface that will stick it to the clot. We also want to improve the efficiency of encapsulating the plasmin in the liposome. Right now, about 15 percent of the plasmin gets into the liposomewe're aiming for 50 percent."
###
Kandadai, a postdoctoral fellow in the UC Department of Emergency Medicine, will present the abstract, "Plasmin loaded echogenic liposomes: A Novel Thrombolytic," at the Society for Academic Emergency Medicine annual meeting May 14-18 in Atlanta. Meunier, a research assistant professor of emergency medicine, is also a co-author.
[ | E-mail | Share ] ?
AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.
Source: http://www.eurekalert.org/pub_releases/2013-05/uoca-sfp051513.php
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Russia, U.S. plot peace talks for Syria
The United States and Russia are 'finding this common ground' on the conflict in Syria, said U.S. Secretary of State John Kerry. The two countries are now preparing for a peace conference in Geneva in June, which Syria is expected to attend. ?
Russian Foreign Minister Sergey Lavrov, right, and U.S. Secretary of State John Kerry shake hands during a joint press conference in Moscow , Russia, May 8, 2013. Russian and U.S. officials are working together to broker peace in the beleaguered Middle Eastern nation of Syria.
AP Photo/Misha Japaridze
EnlargeU.S. Secretary of State John Kerry and Russian Foreign Minister Sergei Lavrov said on Wednesday they believed they could pull off peace talks on Syria, where their nations back opposing sides in a war that may have cost 120,000 lives.
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Differences between Russia, a main ally of President Bashar al-Assad, and the United States, which supports those trying to topple him, have long obstructed U.N. action on the turmoil that has convulsed Syria?for more than two years.
But last week Kerry and Lavrov announced plans to hold a peace conference now expected to take place in Geneva in June.
"Both of us are ... very, very hopeful that within a short period of time, pieces will come together so that the world, hopefully, will be given an alternative to the violence and destruction that is taking place in Syria?at this moment," Kerry said at a news conference after meeting Lavrov in Kiruna, Sweden.
"I would very much share the assessments just presented by John," Lavrov said.
He said Moscow and Washington were trying to mobilize support for the negotiations from Syria's government and opposition, as well as other countries concerned.
Kerry said the peace drive was based on a deal that has stayed a dead letter since it was announced in Geneva in June 2012 for the creation of a transitional government in Syria?"with full executive authority by mutual consent" - ambiguous wording that deliberately left Assad's future role unclear.?
'Working together'
"That's what we're working toward and I don't think it's insignificant that at this moment in time we are finding this common ground and working closely together," Kerry said.
Syrian revolutionaries have previously demanded Assad's removal before any talks on the country's future. The main Western-backed opposition coalition is due to meet in Istanbul to consider whether to attend the new Geneva talks.
A Western diplomat in Paris said the Friends of Syria, an anti-Assad group of mainly Western and Arab countries, would meet in Jordan on May 22 to discuss the U.S.-Russian initiative. A U.S. State Department spokesman said Kerry planned to attend the meeting in Jordan but said he could not confirm the date.
Kerry and Lavrov, who met for an hour on Tuesday night on the sidelines of a meeting of the eight-nation Arctic Council, emphasised they were working in tandem on the Syria?plan.
Syrian Information Minister Omran Zoabi said on Tuesday that Assad's government, fighting an insurgency that threatens to draw in Syria's neighbours, wanted specifics on the proposed conference before it decides whether to participate.
Kerry and Lavrov both said they expected Syria?to attend.
Despite a push from some U.S. lawmakers for Washington to provide military aid to Syria's rebels - and to consider some military involvement such as a no-fly zone - President Barack Obama's administration wants a peaceful resolution to the war.
The pro-opposition Syrian Observatory for Human Rights, a British-based monitoring group, said on Tuesday that at least 94,000 people had been killed in the Syrian conflict, but that the real death toll was likely to be as high as 120,000.
(Additional reporting by John Irish in Paris; Editing by Alistair Lyon and Bill Trott)
Source: http://rss.csmonitor.com/~r/feeds/csm/~3/hqGs1eUyVa8/Russia-U.S.-plot-peace-talks-for-Syria
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